Histopathological characterization of experimentally induced cutaneous loxoscelism in rabbits inoculated with Loxosceles similis venom
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چکیده
منابع مشابه
Histopathological characterization of experimentally induced cutaneous loxoscelism in rabbits inoculated with Loxosceles similis venom
Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus. Recent studies show that atheromatous plaque is prone to thrombosis due to endothelial cell apoptosis. To the best of our knowledge, there are no reports of microsco...
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5 Guilherme Martins1, Maira Oliveira1, Ana Flávia Botelho1, Conrado Gamba2, Clara Duarte3, 6 Adriane Bicalho1, Geovanni Cassali2, Alfredo Goes2, Carlos Chávez-Olórtegui2, Benito 7 Soto-Blanco1 and Marilia Melo1* 8 9 1 Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Minas 10 Gerais, Brazil; [email protected] (GM); [email protected] (MO);...
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Envenomation by Loxosceles spider can result in two clinical manifestations: cutaneous and systemic loxoscelism, the latter of which includes renal failure. Although incidence of renal failure is low, it is the main cause of death, occurring mainly in children. The sphingomyelinase D (SMase D) is the main component in Loxosceles spider venom responsible for local and systemic manifestations. Th...
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ژورنال
عنوان ژورنال: Journal of Venomous Animals and Toxins including Tropical Diseases
سال: 2012
ISSN: 1678-9199
DOI: 10.1590/s1678-91992012000300005